Can “Mad Dog Mattis” activate/pacify soldiers with remotely-controlled Theranos microneedle?

Medical device for analyte monitoring and drug delivery
The invention relates to an ingestible, implantable or wearable medical device comprising a microarray which comprises a bioactive agent capable of interacting with a disease marker biological analyte; a reservoir which comprises at least one therapeutic agent and is capable of releasing the therapeutic agent(s) from the medical device; and a plurality of microchips comprising a microarray scanning device capable of obtaining physical parameter data of an interaction between the disease marker biological analyte with the bioactive agent; a biometric recognition device capable of comparing the physical parameter data with an analyte interaction profile; optionally a therapeutic agent releasing device capable of controlling release of the therapeutic agent from the reservoirs; an interface device capable of facilitating communications between the microarray scanning device, biometric recognition device and the therapeutic agent releasing device; and an energy source to power the medical device. Specifically, the invention relates to a medical device capable of detecting an analyte in a bodily fluid comprising at least one microneedle capable of obtaining a sample of a bodily fluid, a first microchannel through which the sample flows and is in fluid communication with the at least one microneedle, a second microchannel in fluid communication with the first microchannel, through which a buffer flows, wherein the second channel comprises a microarray with a bioactive agent, a microarray scanning device to detect an interaction between the bioactive agent and the analyte in the bodily fluid; and an interface device.

Inventor: Elizabeth A. Holmes
Current Assignee: Theranos Ip Company LLC
Original Assignee: Theranos Inc
Priority date: 2003-09-11

How did Elizabeth Holmes have the technical and business knowledge and the motivation as a Stanford sophomore to dropout and pursue building Theranos for the next ten years?

Joseph Philleo, USC Economics
Updated Nov 5, 2015 · Author has 734 answers and 3.8m answer views
Well, prior to dropping out of Stanford, Miss Holmes:

• Learned Mandarin Chinese
• Lived in China for a bit and sold C++ Compilers to Chinese Universities
• Got accepted to Stanford University
• Was named a “President’s Scholars” her Freshman year and was awarded $3,000 for research.
• Used her fluency in Chinese to win an “internship at the Genome Institute of Singapore.
• The Institute was working on developing new methods to detect the SARS coronavirus in blood or nasal swabs.”
• Returned to Stanford and wrote a patent application “that described a wearable patch that could monitor variables in the patient’s blood, administer a medication, and adjust its dosage to achieve a desired effect. Further, a cellphone chip could be put on this patch for remote monitoring—so-called telemedicine.”
• “Filed the patent application in September 2003, as Medical device for analyte monitoring and drug delivery.”
• Won her parents permission to use her college tuition for the creation of Theranos
• Convinced others (her professor, brother, Mr. Balwani) to join her.

I’d say she’s just as qualified as anyone else to start a company.

Furthermore, for the first two / three years of its founding, Theranos wasn’t actually a blood testing company. It was a company trying to pursue Miss. Holmes’s “cellphone chip” patent. However, that ended up not working out (due to economics – technologically I think it was okay).

So, rather than go under, Theranos decided to pivot. To stay alive they utilized a few pretty good scientists (most notably, Dr. Gibbons who committed suicide in 2013) and began doing blood tests for clinical trials. This apparently provided them enough revenue and time to continue working on their “revolutionary” blood testing procedures.

In 2013, the company came out of stealth mode and was apparently brimming with technology and patents, pronouncing themselves a success. By then, the company was pretty expansive (over 500 employees). While Miss. Holmes may have been involved in the direction of research, her role was (likely) primarily business and managerial. With respect to this role, it seems Miss Holmes has done a good job (until recently). She’s been able to build an impressive (albeit old and unfit) Board of Directors, partner with Walgreens, and create massive publicity around her company.

That being said – the future of Theranos will depend entirely on the validity of its technology. If it works, great – then the WSJ owes the company an apology. If not, no amount of business acumen or media hype can make gold out of garbage.


More on Theranos from personal experience:

“Arizona is the state used for the blood draw stations in all of the Walgreen Drug Stores. It is inconceivable to me that a 19 year old college drop-out was able to do what she did without this being a massive setup and she was the figurehead. Think about it, Holmes is young, pretty, intelligent and dating a man 20 years her senior. Her mom and dad not only lived in Washington DC but worked for the government in various capacities. It has all the makings of a movie straight out of Hollywood.”

Quora – Sunny Balwani:

Balwani Background:

Theranos – Wikipedia:

Elizabeth Holmes, Father & Mother – Wikipedia:

Mini Bio of Elizabeth Holmes:

Elizabeth Holmes – The Rise and fall of Theranos!

“My Actual Blood Draw in the Walgreens Stores:

Theranos holds several patents, but is mainly known for its ground-breaking blood test techniques. Unlike the blood testing procedures carried out at the commercial diagnostic labs of today which need a vial of blood as sample, the Theranos Wellness Centers require only a miniscule amount of blood drawn via a painless prick for diagnostic purposes. Also, these tests are done at a fraction of the current costs and offers faster results. Some tests like the ones for cholesterol cost as little as $3.40

What this article doesn’t say is this: When a patient goes in for a blood draw, rarely is it for just one test. (Only exceptions are glucose or A1C draws for diabetic’s glucose levels or to identify any one test such as for herpes). When the patient arrives (in this case me), with their prescription for the lab tests, the patient does pay cash and it’s significantly lower than what the co-pay may be covered under insurance. What happens then is the technician takes the patient into the drawing station, looks at the lab request and then says, “Oh, your doctor is requesting some tests that I have to draw blood from your vein. Since I are making the vein stick, I’ll just draw enough blood for all the tests ordered.”

That is why and when I was suspect. I had my own lab tests done by Theranos one time only and figured out that it was a bit of a ruse. Theranos couldn’t do any standard blood tests with a finger stick so told the patients that they needed to do a vein stick instead. I told my doctor about my experience and he promptly said, “that is the last time I’m sending anyone there. I thought Theranos could do all the blood testing with a finger stick. That is what the sales rep told me”.

The big hype was that they had a special needle and equipment that only required using a finger stick. Well, I wonder other than testing for glucose or possibly herpes, how they could have possibly obtained enough blood to do any standard chem panels or blood testing of any type. When I asked that question of the technician, she stammered around a bit and said, we have very sophisticated equipment that only needs a small amount of blood to do the analysis. When I received my lab results, everything showed within normal limits, but then remember, I had a stick in my vein not a finger stick.”



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